Microstructural substrate in RVOT for Brugada syndrome

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Electrical Substrate Elimination in 135 Consecutive Patients With Brugada Syndrome.

BACKGROUND There is emerging evidence that localization and elimination of abnormal electric activity in the epicardial right ventricular outflow tract may be beneficial in patients with Brugada syndrome. METHODS AND RESULTS A total of 135 symptomatic Brugada syndrome patients having implantable cardiac defibrillator were enrolled: 63 (group 1) having documented ventricular tachycardia (VT)/v...

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Correlation between functional and ultrastructural substrate in Brugada syndrome

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Brugada Syndrome Phenotype Elimination by Epicardial Substrate Ablation.

BACKGROUND Whether Brugada syndrome (BrS) depends on functional epicardial substrates, which may be definitively eliminated by radiofrequency ablation, remains unknown. METHODS AND RESULTS Patients with BrS underwent epicardial mapping to identify areas of abnormal electrograms as target for radiofrequency ablation. Substrate identification consisted in mapping right ventricle epicardial surf...

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Brugada syndrome.

Brugada syndrome is a rare cardiac arrhythmia characterized by electrocardiographic right bundle branch block and persistent ST-segment elevation in the right precordial leads. It is associated with ventricular fibrillation and a high risk for sudden cardiac death, predominantly in younger males with structurally normal hearts. Patients can remain asymptomatic, and electrocardiographic patterns...

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Brugada syndrome.

First introduced as a new clinical entity in 1992, the Brugada syndrome is associated with a relatively high risk of sudden death in young adults, and occasionally in children and infants. Recent years have witnessed a striking proliferation of papers dealing with the clinical and basic aspects of the disease. Characterized by a coved-type ST-segment elevation in the right precordial leads of t...

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ژورنال

عنوان ژورنال: Archives of Cardiovascular Diseases Supplements

سال: 2018

ISSN: 1878-6480

DOI: 10.1016/j.acvdsp.2018.02.140